How Long Can I Take St. John’s Wort?

St. John’s wort (Hypericum perforatum) is an herbal remedy that has been traditionally used for various conditions, including the treatment of mild to moderate depression. If you are considering using St. John’s wort, it is important to understand the recommended duration of use and the available safety data. This article will provide an overview of the topic based on information from reputable sources.

Generally Considered Safe for Short-Term Use

According to the Mayo Clinic, St. John’s wort is generally considered safe when taken orally for up to 12 weeks in appropriate doses. It is commonly used for short-term treatment of mild to moderate depression. However, it is essential to follow the recommended dosage guidelines and consult with a healthcare professional.

Limited Information on Long-Term Safety

While St. John’s wort has been extensively studied for its short-term effects, there is limited information available on its long-term safety. A study published in Phytomedicine evaluated the long-term effects of St. John’s wort treatment in patients with mild to moderate depression. The study found that the intake of St. John’s wort extract for up to 1 year did not result in any significant changes in clinical chemistry or electrocardiogram recordings. However, more research is needed to establish the safety and effectiveness of prolonged use of St. John’s wort.

Consultation with a Healthcare Professional

Before starting or continuing the use of St. John’s wort, it is strongly advised to consult with a healthcare professional. This is particularly important if you have any underlying medical conditions or if you are taking other medications. A healthcare professional can evaluate your specific situation and provide personalized guidance.

In conclusion, St. John’s wort is generally considered safe for short-term use in appropriate doses. However, due to limited long-term safety data, it is essential to consult with a healthcare professional before considering prolonged use. They can provide the necessary guidance based on your individual circumstances.

Sources

  1. Mayo Clinic. (Retrieved from: https://www.mayoclinic.org/drugs-supplements-st-johns-wort/art-20362212)
  2. Mount Sinai – New York. (Retrieved from: https://www.mountsinai.org/health-library/herb/st-johns-wort)
  3. Brattström, A. (2009). Long-term effects of St. John’s wort (Hypericum perforatum) treatment: a 1-year safety study in mild to moderate depression. Phytomedicine, 16(4), 277-83. doi: 10.1016/j.phymed.2008.12.023 (Retrieved from: https://pubmed.ncbi.nlm.nih.gov/19299116/)

FAQs

Is St. John’s wort safe for long-term use?

There is limited information available regarding the long-term safety of St. John’s wort. While it is generally considered safe for short-term use, more research is needed to determine its safety and effectiveness for prolonged use.

Can I take St. John’s wort for more than 12 weeks?

St. John’s wort is commonly used for short-term treatment of mild to moderate depression. It is generally recommended to use it for up to 12 weeks. Beyond that, it is important to consult with a healthcare professional for guidance.

Are there any risks associated with long-term use of St. John’s wort?

Since the long-term safety of St. John’s wort is not well-established, there may be potential risks associated with prolonged use. It is essential to consult with a healthcare professional to assess any potential risks or interactions with other medications or underlying medical conditions.

Can I use St. John’s wort as a long-term maintenance treatment for depression?

St. John’s wort has been studied for its effectiveness in treating mild to moderate depression. However, its suitability as a long-term maintenance treatment is still under investigation. It is important to consult with a healthcare professional to discuss the best treatment options for managing your depression in the long term.

Are there any side effects associated with long-term use of St. John’s wort?

St. John’s wort is generally well-tolerated, but like any medication or herbal supplement, it can have side effects. The specific side effects associated with long-term use of St. John’s wort are not well-documented. It is advisable to monitor your response to the herb and consult with a healthcare professional if you experience any adverse effects.

Should I consult a healthcare professional before taking St. John’s wort long-term?



Yes, it is crucial to consult with a healthcare professional before considering long-term use of St. John’s wort. They can evaluate your medical history, current medications, and individual circumstances to provide personalized guidance and ensure it is safe and appropriate for you.

Can I combine St. John’s wort with other medications for long-term use?

St. John’s wort has the potential to interact with certain medications, including antidepressants, birth control pills, and blood thinners. It is essential to consult with a healthcare professional to assess potential interactions and determine if combining St. John’s wort with other medications is safe for long-term use.

Can I stop taking St. John’s wort abruptly after long-term use?

If you have been taking St. John’s wort for an extended period, it is generally recommended to gradually reduce the dosage under the guidance of a healthcare professional. Abruptly stopping the use of St. John’s wort may lead to discontinuation symptoms or a relapse of symptoms. A healthcare professional can provide appropriate instructions for tapering off the herb.